Chronic Pain & Wound Healing


Photobiomodulation (PBM) can relieve pain and stimulate wound healing. PBM has been shown to reduce pain immediately after treatment of acute neck pain and up to 22 weeks after completion of treatment of chronic neck pain. In regards to fibromyalgia, PBM has been shown to improve pain threshold and tenderness. In regards to carpal tunnel syndrome (CTS), PBM has been shown to alleviate pain and symptoms, improve functional ability, finger and hand strength for mild and moderate CTS patients. In regards to musculoskeletal health, PBM may enhance the oxidative energy metabolic capacity of different types of muscle fibers, and be used to enhance the aerobic potential of skeletal muscle. In regards to Tennis Elbow (lateral epicondylitis), PBM in addition to exercise has been shown to effectively relieve pain, and improve the grip strength and subjective rating of physical function. Furthermore, PBM has been shown to successfully induce wound healing in non-healing defects, burns, amputation injuries, skin grafts, infected wounds, trapping injuries, radiotherapy-induced ulcers and oral mucositis.


Randomized, blinded, controlled trial on effectiveness of photobiomodulation therapy and exercise training in the fibromyalgia treatment.
da Silva MM1, Albertini R2, de Tarso Camillo de Carvalho P1, Leal-Junior ECP1, Bussadori SK1, Vieira SS2, Bocalini DS3, de Oliveira LVF4, Grandinetti V1, Silva JA Jr1, Serra AJ5.
https://www.ncbi.nlm.nih.gov/pubmed/29170901
Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials.
Chow RT1, Johnson MI, Lopes-Martins RA, Bjordal JM.
https://www.ncbi.nlm.nih.gov/pubmed/19913903
In vivo low-level light therapy increases cytochrome oxidase in skeletal muscle.
Hayworth CR1, Rojas JC, Padilla E, Holmes GM, Sheridan EC, Gonzalez-Lima F.
https://www.ncbi.nlm.nih.gov/pubmed/20408982
Carpal tunnel syndrome treated with a diode laser: a controlled treatment of the transverse carpal ligament.
Chang WD1, Wu JH, Jiang JA, Yeh CY, Tsai CT.
https://www.ncbi.nlm.nih.gov/pubmed/19025407
Effects of 904-nm low-level laser therapy in the management of lateral epicondylitis: a randomized controlled trial.
Lam LK1, Cheing GL.
https://www.ncbi.nlm.nih.gov/pubmed/17508839
Low level laser therapy in oral mucositis: a pilot study.
Cauwels RG1, Martens LC.
https://www.ncbi.nlm.nih.gov/pubmed/21473845
Low level laser therapy (LLLT) as an effective therapeutic modality for delayed wound healing.
Hawkins D1, Houreld N, Abrahamse H.
https://www.ncbi.nlm.nih.gov/pubmed/16387711
Low intensity laser irradiation in the treatment of recalcitrant radiation ulcers in patients with breast cancer--long-term results of 3 cases.
Schindl A1, Schindl M, Pernerstorfer-Schön H, Mossbacher U, Schindl L.
https://www.ncbi.nlm.nih.gov/pubmed/10721863
Julian Loh